AIM: To investigate the availability and safety of phacoemulsification combined with goniosynechialysis for patients with persistent high intraocular pressure in acute primary angle-closure glaucoma.METHODS: Retrospective study. The clinical data of 31 patients (31 eyes) with persistent high intraocular pressure of primary angle-closure glaucoma treated in our center from January 2018 to April 2022 were collected. Each patient underwent phacoemulsification combined with goniosynechialysis after removing the cloudy corneal epithelium and recording the best corrected visual acuity(BCVA), intraocular pressure, and the appearance of the anterior chamber All data were analyzed statistically. RESULTS: After surgical treatment, the best corrected visual acuity was 0.70 (0.30, 0.90) 1 week, 0.30 (0.20, 0.50), 1 month, 0.30 (0.10,0.40), 3 months after surgery, and 0.30 (0.20,0.40) at the last follow-up, respectively, and it was significantly higher than preoperative 1.40 (1.10,2.00) (P < 0.01). The intraocular pressure was 16.20 (12.30,19.40) mmHg, 11.90 (10.80,14.20) mmHg, 13.80 (12.10,16.20) mmHg, 0.30 (0.10,0.40) mmHg and 11.70 (10.40, 12.40) mmHg at 1 day, 1week, 1 month, 3 months, and the last follow-up, and were significantly lower than preoperative 38.60(33.90,42.80)mmHg (P <0.01 ). The central anterior chamber depth and anterior chamber angle width were significantly different between pre-operation and each visit time after the operation (P < 0.01).CONCLUSION: Phacoemulsification combined with goniosynechialysis is a safe and feasible method to treat patients of acute primary angle-closure glaucoma eyes with persistent high intraocular pressure, which can reopen the anterior chamber angle, control intraocular pressure, and improve the visual acuity.

Acute attack of acute primary angle-closure glaucoma，Persistent high intraocular pressure，Phacoemulsification，Goniosynechialysis

Kun He, Pengfei Tian, Suyun Yang(2024). The Effect of Persistent High Intraocular Pressure Treated by Phacoemulsification Combined with Goniosynechialysis in Eyes with Acute Primary Angle- closure Glaucoma. Medical Journal of Ophthalmology, Volume 1, Issue 2, Page 1-7, Publish Date: 2024-03-18